Bear, Christine E.: search on Z-Library

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1

Comprehensive mapping of cystic fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site

Molinski, Steven V., Shahani, Vijay M., Subramanian, Adithya S., MacKinnon, Stephen S., Woollard, Geoffrey, Laforet, Marcon, Laselva, Onofrio, Morayniss, Leonard D., Bear, Christine E., Windemuth, And

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

2

The Strong Heart Water Study: Informing and designing a multi-level intervention to reduce arsenic exposure among private well users in Great Plains Indian Nations

Thomas, Elizabeth D., Gittelsohn, Joel, Yracheta, Joseph, Powers, Martha, O'Leary, Marcia, Harvey, David E., Red Cloud, Reno, Best, Lyle G., Black Bear, Annabelle, Navas-Acien, Ana, George, Christine

Journal:

Science of The Total Environment

Year:

2019

Language:

english

File:

PDF, 1.54 MB

english, 2019

3

Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

Wong, Amy P, Bear, Christine E, Chin, Stephanie, Pasceri, Peter, Thompson, Tadeo O, Huan, Ling-Jun, Ratjen, Felix, Ellis, James, Rossant, Janet

Journal:

Nature Biotechnology

Year:

2012

Language:

english

File:

PDF, 1.69 MB

english, 2012

4

Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms

Beaudoin, Trevor, Stone, Tracy A., Glibowicka, Miroslawa, Adams, Christina, Yau, Yvonne, Ahmadi, Saumel, Bear, Christine E., Grasemann, Hartmut, Waters, Valerie, Deber, Charles M.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.86 MB

english, 2018

5

High bone density in young Hutterite children

Christine L. Wey, Tianna Beare, Kristin Biskeborn, Teresa Binkley, Lacey Arneson, Bonny Specker

Journal:

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

6

An organoid model to assay the role of CFTR in the human epididymis epithelium

Leir, Shih-Hsing, Yin, Shiyi, Kerschner, Jenny L., Xia, Sunny, Ahmadi, Saumel, Bear, Christine, Harris, Ann

Journal:

Cell and Tissue Research

Year:

2020

File:

PDF, 659 KB

2020

7

Directed differentiation of cholangiocytes from human pluripotent stem cells

Ogawa, Mina, Ogawa, Shinichiro, Bear, Christine E, Ahmadi, Saumel, Chin, Stephanie, Li, Bin, Grompe, Markus, Keller, Gordon, Kamath, Binita M, Ghanekar, Anand

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 3.54 MB

english, 2015

8

Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis

Kong, Sek, Sahin, Mustafa, Collins, Christin D, Wertz, Mary H, Campbell, Malcolm G, Leech, Jarrett D, Krueger, Dilja, Bear, Mark F, Kunkel, Louis M, Kohane, Isaac S

Journal:

Molecular Autism

Year:

2014

Language:

english

File:

PDF, 330 KB

english, 2014

9

The Role of the Gut Microbiota in Dietary Interventions for Depression and Anxiety

Bear, Tracey L K, Dalziel, Julie E, Coad, Jane, Roy, Nicole C, Butts, Christine A, Gopal, Pramod K

Journal:

Advances in Nutrition: An International Review Journal

Year:

2020

File:

PDF, 1003 KB

2020

10

Generation of diffuse intrinsic pontine glioma mouse models by brainstem targeted in utero electroporation

Patel, Smruti K, Hartley, Rachel M, Wei, Xin, Furnish, Robin, Escobar-Riquelme, Fernanda, Bear, Heather, Choi, Kwangmin, Fuller, Christine, Phoenix, Timothy N

Journal:

Year:

2019

File:

PDF, 2.10 MB

2019

11

Generation of diffuse intrinsic pontine glioma mouse models by brainstem targeted in utero electroporation

Patel, Smruti K, Hartley, Rachel M, Wei, Xin, Furnish, Robin, Escobar-Riquelme, Fernanda, Bear, Heather, Choi, Kwangmin, Fuller, Christine, Phoenix, Timothy N

Journal:

Year:

2019

Language:

english

File:

PDF, 2.10 MB

english, 2019

12

Employeesâ emotional reactions to digitally enabled work events

Beare, Elaine Christine, OâRaghallaigh, Paidi, McAvoy, John, Hayes, Jeremy

Journal:

Journal of Decision System

Year:

2020

File:

PDF, 910 KB

2020

13

A Therapy for Most with Cystic Fibrosis

Bear, Christine E.

Journal:

Year:

2020

Language:

english

File:

PDF, 61 KB

english, 2020

14

Identification Of The NHERF2 Binding Site For The Chloride/Proton Transporter ClC-5

Wellhauser, Leigh, Penmatsa, Himabindu, Naren, Anjaparavanda P., Bear, Christine E.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

15

Nucleotides bind to the C-terminus of ClC-5

Wellhauser, Leigh, Kuo, Hsin-Hen, Stratford, Fiona L. L., Ramjeesingh, Mohabir, Huan, Ling-Jun, Luong, Winnie, Li, Canhui, Deber, Charles M., Bear, Christine E.

Journal:

Biochemical Journal

Year:

2006

Language:

english

File:

PDF, 302 KB

english, 2006

16

HGG-13. DETERMINING REGIONAL DIFFERENCES IN HIGH-GRADE GLIOMA VASCULATURE PHENOTYPE

Wei, Xin, Hartley, Rachel, Bear, Heather, Fuller, Christine, Phoenix, Timothy N

Journal:

Year:

2019

Language:

english

File:

PDF, 100 KB

english, 2019

17

Activity of lumacaftor is not conserved in zebrafish Cftr bearing the major cystic fibrosis‐causing mutation

Laselva, Onofrio, Erwood, Steven, Du, Kai, Ivakine, Zhenya, Bear, Christine E.

Journal:

FASEB BioAdvances

Year:

2019

Language:

english

File:

PDF, 694 KB

english, 2019

18

Sensitizing T-lymphocytes for adoptive immunotherapy by vaccination with wild-type or cytokine gene-transduced melanoma

Kenneth A. Lipshy, Paul J. Kostuchenko, Giselle G. Hamad, Christin E. Bland, Sandra K. Barrett, Harry D. Bear

Journal:

Annals of Surgical Oncology

Year:

1997

Language:

english

File:

PDF, 1.13 MB

english, 1997

19

ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5

Leigh Wellhauser, Christina D’Antonio, Christine E. Bear

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 477 KB

english, 2010

20

Cystic Fibrosis Transmembrane Conductance Regulator Modulates Neurosecretory Function in Pulmonary Neuroendocrine Cell-Related Tumor Cell Line Models

Pan, Jie, Bear, Christine, Farragher, Susan, Cutz, Ernest, Yeger, Herman

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2002

Language:

english

File:

PDF, 257 KB

english, 2002

21

Functional Rescue of F508del-CFTR Using Small Molecule Correctors

Molinski, Steven, Eckford, Paul D. W., Pasyk, Stan, Ahmadi, Saumel, Chin, Stephanie, Bear, Christine E.

Journal:

Frontiers in Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

22

Expression of CFTR and Cl − conductances in cells of pulmonary neuroepithelial bodies

Yeger, Herman, Pan, Jie, Fu, Xiao Wen, Bear, Christine, Cutz, Ernest

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

2001

Language:

english

File:

PDF, 443 KB

english, 2001

23

Sodium-dependent taurocholate uptake by isolated rat hepatocytes occurs through an electrogenic mechanism

Christine E. Bear, Joseph S. Davison, Eldon A. Shaffer

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1987

Language:

english

File:

PDF, 541 KB

english, 1987

24

ATPase assay of purified, reconstituted CFTR protein

Ilana Kogan, Mohabir Ramjeesingh, Christine E. Bear

Journal:

Journal of Cystic Fibrosis

Year:

2004

Language:

english

File:

PDF, 65 KB

english, 2004

25

Role of SLC6A14 as a Modifier of Cystic Fibrosis Phenotype

Ahmadi, Saumel, Luk, Catherine, Chung, Timothy, Mangat, Rupinder, Rommens, Johanna, Bear, Christine

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 41 KB

english, 2013

26

Identification and Validation of Hits from High Throughput Screens for CFTR Modulators

Pasyk, Stan, Molinski, Steven, Yu, Wilson, D.W. Eckford, Paul, E. Bear, Christine

Journal:

Current Pharmaceutical Design

Year:

2012

Language:

english

File:

PDF, 933 KB

english, 2012

27

Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants

Laselva, Onofrio, Bartlett, Claire, Popa, Alec, Ouyang, Hong, Gunawardena, Tarini N.A., Gonska, Tanja, Moraes, Theo J., Bear, Christine E.

Journal:

Journal of Cystic Fibrosis

Year:

2020

File:

PDF, 3.45 MB

2020

28

Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance

Norbert Kartner, John W. Hanrahan, Tim J. Jensen, A.Leonard Naismith, Shizhang Sun, Cameron A. Ackerley, Evangelica F. Reyes, Lap-Chee Tsui, Johanna M. Rommens, Christine E. Bear, John R. Riordan

Journal:

Year:

1991

Language:

english

File:

PDF, 2.59 MB

english, 1991

29

Evaluation of the membrane-spanning domain of ClC-2

Ramjeesingh, Mohabir, Li, Canhui, She, Yi-Min, Bear, Christine E.

Journal:

Biochemical Journal

Year:

2006

Language:

english

File:

PDF, 892 KB

english, 2006

30

Synthesis and characterization of a photoaffinity labelling probe based on the structure of the cystic fibrosis drug ivacaftor

Hamilton, C. Michael, Hung, Maurita, Chen, Gang, Qureshi, Zafar, Thompson, John R., Sun, Bingyun, Bear, Christine E., Young, Robert N.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.36 MB

english, 2018

31

Direct Interaction Of A Small Molecule Modulator With G551D-CFTR, A Cystic Fibrosis Causing Mutation Associated With Severe Disease

Pasyk, Stan, Li, Canhui, Ramjeesingh, Mohabir, Bear, Christine E.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

32

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Eckford, Paul D. W., Li, Canhui, Bear, Christine E.

Journal:

Journal of Visualized Experiments

Year:

2015

Language:

english

File:

PDF, 959 KB

english, 2015

33

Current insights into the role of PKA phosphorylation in CFTR channel activity and the pharmacological rescue of cystic fibrosis disease-causing mutants

Chin, Stephanie, Hung, Maurita, Bear, Christine E.

Journal:

Cellular and Molecular Life Sciences

Year:

2017

Language:

english

File:

PDF, 803 KB

english, 2017

34

Structural effects of extracellular loop mutations in CFTR helical hairpins

Chang, Yuan-Heng, Stone, Tracy A., Chin, Stephanie, Glibowicka, Mira, Bear, Christine E., Deber, Charles M.

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2018

Language:

english

File:

PDF, 1.80 MB

english, 2018

35

ATP depletion inhibits the endocytosis of ClC-2

Sonja U. Dhani, Patrick Kim Chiaw, Ling-Jun Huan, Christine E. Bear

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 306 KB

english, 2008

36

Role of intramolecular and intermolecular interactions in ClC channel and transporter function

Sonja U. Dhani, Christine E. Bear

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 260 KB

english, 2006

37

Amelioration of Intestinal Disease Severity in Cystic Fibrosis Mice Is Associated with Improved Chloride Secretory Capacity

Gyömörey, Katalin, Rozmahel, Richard, Bear, Christine E

Journal:

Pediatric Research

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

38

Testing gene therapy vectors in human primary nasal epithelial cultures

Cao, Huibi, Ouyang, Hong, Ip, Wan, Du, Kai, Duan, Wenming, Avolio, Julie, Wu, Jing, Duan, Cathleen, Yeger, Herman, Bear, Christine E, Gonska, Tanja, Hu, Jim, Moraes, Theo J

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2015

Language:

english

File:

PDF, 3.65 MB

english, 2015

39

Generation of Induced Progenitor-like Cells from Mature Epithelial Cells Using Interrupted Reprogramming

Guo, Li, Karoubi, Golnaz, Duchesneau, Pascal, Shutova, Maria V., Sung, Hoon-Ki, Tonge, Peter, Bear, Christine, Rogers, Ian, Nagy, Andras, Waddell, Thomas K.

Journal:

Stem Cell Reports

Year:

2017

Language:

english

File:

PDF, 5.69 MB

english, 2017

40

SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion

Ahmadi, Saumel, Xia, Sunny, Wu, Yu-Sheng, Di Paola, Michelle, Kissoon, Randolph, Luk, Catherine, Lin, Fan, Du, Kai, Rommens, Johanna, Bear, Christine

Journal:

Year:

2018

Language:

english

File:

PDF, 20.05 MB

english, 2018

41

The CFTR Mutation c.3453G > C (D1152H) Confers an Anion Selectivity Defect in Primary Airway Tissue that Can be Rescued by Ivacaftor

Laselva, Onofrio, Moraes, Theo J., He, Gengming, Bartlett, Claire, SzÃ rics, Ida, Ouyang, Hong, Gunawardena, Tarini N. A., Strug, Lisa, Bear, Christine E., Gonska, Tanja

Journal:

Journal of Personalized Medicine

Year:

2020

File:

PDF, 377 KB

2020

42

Contrast baths: what do we know about their use?

Donna Breger Stanton, Jane Bear-Lehman, Mark Graziano, Christine Ryan

Journal:

Journal of Hand Therapy

Year:

2003

Language:

english

File:

PDF, 90 KB

english, 2003

43

A Monomer Is the Minimum Functional Unit Required for Channel and ATPase Activity of the Cystic Fibrosis Transmembrane Conductance Regulator †

Ramjeesingh, Mohabir, Li, Canhui, Kogan, Ilana, Wang, Yanchun, Huan, Ling-Jun, Bear, Christine E.

Journal:

Year:

2001

Language:

english

File:

PDF, 85 KB

english, 2001

44

Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains

Laselva, Onofrio, Molinski, Steven, Casavola, Valeria, Bear, Christine E.

Journal:

Molecular Pharmacology

Year:

2018

Language:

english

File:

PDF, 3.65 MB

english, 2018

45

Cover Image, Volume 86, Issue 8

Molinski, Steven V., Shahani, Vijay M., Subramanian, Adithya S., MacKinnon, Stephen S., Woollard, Geoffrey, Laforet, Marcon, Laselva, Onofrio, Morayniss, Leonard D., Bear, Christine E., Windemuth, And

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2018

File:

PDF, 1.31 MB

2018

46

Quaternary Structure of the Chloride Channel ClC-2 †

Ramjeesingh, Mohabir, Li, Canhui, Huan, Ling-Jun, Garami, Elizabeth, Wang, Yanchun, Bear, Christine E.

Journal:

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

47

Hepatocellular water and electrolyte secretion

Bear, Christine E., Shaffer, Eldon A.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1988

Language:

english

File:

PDF, 1.16 MB

english, 1988

48

Evaluating the effect of fishery closures: Lessons learnt from the Plaice Box

Beare, Doug, Rijnsdorp, Adriaan D., Blaesberg, Mette, Damm, Ulrich, Egekvist, Josefine, Fock, Heino, Kloppmann, Matthias, Röckmann, Christine, Schroeder, Alexander, Schulze, Torsten, Tulp, Ingrid, Ulr

Journal:

Journal of Sea Research

Year:

2013

Language:

english

File:

PDF, 1.99 MB

english, 2013

49

The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation

Pasyk, Stan, Molinski, Steven, Ahmadi, Saumel, Ramjeesingh, Mohabir, Huan, Ling-Jun, Chin, Stephanie, Du, Kai, Yeger, Herman, Taylor, Paul, Moran, Michael F., Bear, Christine E.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

50

A novel procedure for the efficient purification of the cystic fibrosis transmembrane conductance regulator (CFTR)

RAMJEESINGH, Mohabir, LI, Canhui, GARAMI, Elizabeth, HUAN, Ling-Jun, HEWRYK, Marek, WANG, Yanchun, GALLEY, Kevin, BEAR, Christine E.

Journal:

Biochemical Journal

Year:

1997

Language:

english

File:

PDF, 383 KB

english, 1997

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